منابع مشابه
Coagulation in Sepsis
Activation of inflammatory and coagulation pathways is an important event in the pathogenesis of sepsis. In sepsis, which can be defined as the disadvantageous systemic host response to infection, the blood coagulation system is triggered. Activation of coagulation and deposition of fibrin as a consequence of inflammation can be considered instrumental in containing inflammatory activity to the...
متن کاملCoagulation activation in sepsis
Sepsis is defined as a systemic inflammatory response syndrome occurring during infection (1). Activation of blood coagulation is a common observation in patients with sepsis (2, 3). Nearly all patients with severe sepsis according to the American College of Chest Physicians (ACCP) criteria (1) display elevated levels of activation products of blood coagulation (4). Since in most cases, no sing...
متن کاملDisseminated intravascular coagulation in sepsis.
Disseminated intravascular coagulation is a frequent complication of sepsis. Coagulation activation, inhibition of fibrinolysis, and consumption of coagulation inhibitors lead to a procoagulant state resulting in inadequate fibrin removal and fibrin deposition in the microvasculature. As a consequence, microvascular thrombosis contributes to promotion of organ dysfunction. Recently, three rando...
متن کاملDisseminated intravascular coagulation in sepsis.
Disseminated intravascular coagulation (DIC) has been considered a rather rare syndrome characterized by severe bleeding. In fact, both of these beliefs are wrong. Bleeding is fairly rare in DIC. The clotting parameters are usually normal unless the DIC is fulminating. It is usually thought that fibrinogen may be low or absent in DIC. However, afibrinogenemia is rare. Fibrinogen is usually high...
متن کاملCoagulation Abnormalities in Acute Pancreatitis
Acute pancreatitis (AP) is a potentially lethal disorder with no specific medical treatment. AP is characterized by a spectrum of symptoms, ranging from a local inflammatory process to the more severe form (acute necrotizing pancreatitis) which is associated with a systemic inflammatory response and a mortality rate of 27-45%. A number of risk factors have been identified for AP including alcoh...
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ژورنال
عنوان ژورنال: Acta Anaesthesiologica Taiwanica
سال: 2015
ISSN: 1875-4597
DOI: 10.1016/j.aat.2014.11.002